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 Source Holders
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Source Holders
HDR1000+ Well Chamber
IVB1000 Well Chamber
Ir-192 Wire Measurement
Ir Wire Loop Measurement
Ir Seeds in Ribbon Measurement
HDR Ir-192 Source Measurement
Metastron Measurement
RAPIDStrand Measurement
I/Pd Seed Measurement
Bard Cartridge
Seed QA
Measurement Justification
Chamber Recal & Upgrade
Calibration Systems
SIRAS System
Seed SourceCheck
 


 




 
 

 

 

 

 

 

 

Source Holders for use with the HDR1000 plus Well Chamber

The HDR1000 Plus Well Chamber, SeeDOS Code 90008, is a good choice for low dose rate isotopes. Ten different isotope source holders are available for all existing low dose rate isotopes.  The HDR 1000 Plus Ion Chamber comes with one isotope insert of your choice.

The IVB1000 Well Chamber, SeeDOS Code 90009, is a good choice for low dose rate brachytherapy sources in fixed long configurations such as RAPID Strand, Interstrand® and Isosleeve. It is also the chamber of choice for all intravascular source trains. A new range of source holders are being introduced for this longer chamber which has a 100mm long sweet spot, unmatched in other available chambers. This provides exceptional precision and accuracy for brachytherapy source activities.

To Go To IVB 1000 (longer) Chamber and new Source Holder Details please click here

NEW (February 2003) New Brachytherapy source measuring and handling systems pdf

NEW (End of January 2003) HDR1000 Well Chamber Brachytherapy Source Calibration pdf Brochure - showing available inserts

NIST traceable ADCL well chamber calibrations are available for all source types and configurations.

For low dose rate brachytherapy, the standard of practice has shifted so that the manufacturer's calibration alone is no longer adequate. "However, it is the responsibility of the institution to verify that this calibration is correct. the institution should compare the manufacturer's stated value with the institution's standard." ref. Comprehensive QA for radiation oncology: Report of AAPM Radiation Therapy Committee Task Group 40 Med. Phys. 21(4):581-618, 1994. The HDR 1000 Plus is that standard!

Individual Seed Calibration for Prostate Cancer Treatment

Source Holder for Single Seed Measurements, SeeDOS Code 70016 This insert has a 1.2mm inner diameter Teflon® tube which positions an individual iodine, palladium, iridium, or gold seed at the most sensitive area of the  HDR 1000 Plus Ion Chamber, SeeDOS Code 90008. The smooth Teflon tube allows easy removal of the seed. Ion chamber calibrations from the University of Wisconsin ADCL are available for iodine and palladium.

Go To I/Pd seed measurements for more detail.

 

Batch Assay Measurements

Source Holder for Seed Batch Assay, SeeDOS Code 70022 LDR brachytherapy treatment for prostate cancer measures high numbers of seeds. A treatment center must sometimes receive up to 500 seeds if several cases are imminent. Individual seed calibration is too time consuming and cumber-some. For these large number of seeds, a random sampling of at least 10% of the seeds should be calibrated.

Multiple seed measurements are performed with the Source Holder for LDR Seed Batch Assay, SeeDOS Code 70022. This source holder holds up to 500 of the iodine or palladium seeds typically used for prostate cancer treatment.

Seeds are positioned at the most sensitive area of the HDR 1000 Plus Ion Chamber. If you have the Source Holder 70016 (above) with an ADCL calibration for the isotope being measured, that calibration can be transferred to Source Holder 70022.

Self absorption resulting from a large number of seeds being placed in the insert is significant. Because of this self absorption, correction factors must be experimentally obtained for each type of LDR seed used. This method is described in detail in Med. Phys. 22 (9) Sept. 1995. Note, a correction factor for iodine and palladium as shown in Fig. 2 of this article, should be determined for each individual well chamber upon receipt of the chamber.

Before each assay procedure, a constancy check should be performed to assure the integrity of the calibration system. This should be done with a long half-life isotope like caesium.


Go To I/Pd seed measurements for more detail.

 

Output Measurement of I-125 RAPID Strand™ Iodine Seeds

A fast and convenient method of performing a quality assurance measurement of your I-125 RAPID Strand™ using the Source Holder, SeeDOS Code 70023 under sterile conditions.

 

  • The sterile insert maintains sterility of the I-125 RAPID Strand™.
     
  • Five seeds are measured simultaneously.
     
  • QA measurements within + 5% of calibrated IMC6711 I-125 Seeds™.
     
  • Short term precision is < 1%.
     
  • No measurable rotational dependence.
     
  • The complete calibration system is lightweight and easily portable for use in a sterile environment.

The I-125 RAPID Strand™ Source Holder, SeeDOS Code 70023 is constructed to simultaneously measure five seeds at one end of the I-125 RAPID Strand™ while the I-125 RAPID Strand™ remains in the spacing jig. The spacing jig is then inverted and the five seeds at the other end are measured. The source holder itself can be sterilized.

To determine the activity of your I-125 RAPID Strand™, a correction factor has been determined. An I-125 RAPID Strand™ containing 10 iodine seeds was obtained and an extensive evaluation was performed with the HDR 1000 Plus Well Chamber and the I-125 RAPID Strand™ Source Holder, SeeDOS Code 70023. Following the evaluation, individual seeds of the I-125 RAPID Strand™ were cut from the strand and individually calibrated. To obtain a correction factor, these measurements were compared to the initial, collective seeds measurements of the intact I-125 RAPID Strand™ in Source Holder 70023. For more details go to "Measurement of I-125 RAPID Strand iodine seeds".

Amersham, I-125 Seeds and RAPID Strand are trademarks of Amersham plc.

 

MICK™ Magazine Cartridges

Source Holder for Measurements of Loaded MICK™ Magazine Cartridges,   SeeDOS Code  70024

 

  • Quality Assurance Measurements for Dose Verification
     
  • No Rotational Dependence
     
  • Fast Measurements
     
  • Iodine or Palladium Seeds

A Source Holder has been designed for the HDR 1000 Plus Brachytherapy Well Chamber which provides a quick and convenient QA measurement of loaded MICK™ Magazine Cartridges. This Source Holder positions the seeds at the centre of the well chamber for quick, reproducible measurements.

There is also a MICK™ Magazine Cartridge seed sterilizer available, please click here.

Download our detailed PDF for information on Mick Applicator Magazine Seed Handling, Loading and Activity Measurement

 

                                                                  

 

Bard EXPRESS Seeding Cartridge

  • Quality Assurance measurements within 5% of calibrated seeds
     
  • Measurement reproducibility better than 1%
     
  • No rotational dependence
     
  • A quick calculation provides the average seed activity

Source holder for Bard EXPRESS Seeding Cartridge, SeeDOS Code 70032 positions loaded cartridges at the most sensitive position of the HDR 1000 Plus Well Chamber, providing a check of the relative activity of the seed held within the cartridge. The source holder accommodates Bard Seeding Cartridges with 2 to 6 seeds and can be gas or steam sterilized.

Bard is a registered trademark of C.R. Bard, Inc.
 

 

Low Dose  Rate (LDR) - Iridium Source Holders

Source Holder for Low Dose Rate 192 Ir Ribbon Seeds, SeeDOS Code 70009 has a 3mm diameter acrylic tube which extends from the top of the insert to the most active area of the chamber. It makes one loop at the active area and extends back to the top of the insert. A collective calibration of the entire ribbon of seeds is obtained. Fourteen iridium seeds spaced one centimetre centre to centre can fit into the active area. Some intravascular brachytherapy sources can be measured in this insert.
Source Holder for Measurement of Iridium Wire Coils, SeeDOS Code 70022 The iridium wire coil is placed in the tube and uniformly compressed to 2mm for measurement at the most sensitive point of the ion chamber. This consistent positioning provides for excellent measurement reproducibility. Short term reproducibility is 0.6%. Linearity over a range of 124 to 2036 MBq is better than 0.1%.
High Dose  Rate (HDR) -  Iridium Source Holder

Source Holder for High Dose Rate Iridium, SeeDOS Code 70010, has a 2.2 mm opening for the catheter. A rubber O-ring secures the catheter with a uniform constricting pressure to prevent any movement of the catheter. The holder positions the source in the centre of the most sensitive position of the HDR 1000 plus Well Chamber.

The calibration procedure is easy and uncomplicated. The time required for calibration is only a fraction of that required for thimble ion chamber techniques.

 

           

 

Caesium-137 Source Holders

Source Holder for Caesium-137 sources, SeeDOS Code 70020 has a 5mm diameter opening and is commonly used with manually loaded caesium sources. A spacer within the source holder positions the caesium insert at the most active area of the chamber. The spacer for positioning the caesium source is removable so that the insert can also be used with some longer caesium sources, and with larger HDR  Ir-192 catheters.
Source Holder for Caesium Remote Afterloading, SeeDOS Code 70003 has a 7.1mm diameter opening. This insert is used with LDR remote afterloading treatment systems. There is no spacer because the afterloading system positions the sources. This insert can also be used with cobalt sources used in some LDR remote afterloading treatment systems.

 

MetastronTM Syringe Source Holder

Source Holder for Measurement of Metastron™ (Strontium-89 Chloride Injection), SeeDOS Code 70026 has been designed for the HDR 1000 Plus Brachytherapy Well Chamber which provides a quick and convenient QA measurement of Metastron vials. Source Holder 70026 for 5cc and 10cc Metastron Syringes, includes one set of two syringe holders, one for a 5cc syringe and one for a 10cc syringe.

 

Metastron is a trademark of Amersham plc
One Inch Lead Shielding Ring, SeeDOS Code 70025. This shielding ring is made of one inch thick lead which surrounds the HDR 1000 Plus Brachytherapy Well Chamber. It is constructed of four interlocking rings to shield the user during measurement.

 

Measuring IBt InterStrand® Sources with the IVB1000 Well Chamber

 

The IBt InterStrand® Source Holder, SeeDOS Code 70049

being inserted into the IVB 1000 Well Chamber

 

  • Fast and easy QA measurements using the IVB 1000 Well Chamber.

 

  • Specially designed source holder for

           International Brachytherapy (IBt)

           InterStrand source trains:

           10 model 1031L  Pd-103 seeds

           10 model 1251L  I-125 seeds

 

  • Correction factor and formula to determine air

           kerma strength is included in the instruction manual.

 

  • Source holder can be gas or steam (autoclaved) sterilized.

 To Go To IVB 1000 Chamber and Source Holder Details please click here    

   

                               

                     

Measuring Imagyn Isosleeve™ Sources with the IVB 1000 Well Chamber

 

The Imagyn Isosleeve™ Source Holder, SeeDOS Code 70050

being inserted into the IVB 1000 Well Chamber

 

  • Fast and easy QA measurements. ADCL calibrations available.

 

  • Specially designed source holder for Imagyn Medical Technologies isosleeve™.

 

  • Correction factor and formula to determine air kerma strength is included      in the instruction manual.

 

  • Source holder can be gas or steam (autoclaved) sterilized.

 

To Go To IVB 1000 Chamber and Source Holder Details please click here

 

Calibrations

SeeDOS offers NIST traceable calibrations from the University of Wisconsin Accredited Dosimetry Calibration Laboratory. You need only one purchase order to cover calibrations, shipping, handling and service.  All instruments are hand carried to the ADCL for calibration.

High Dose Rate Calibrations Available

HDR 192Ir

Low Dose Rate Calibrations Available

Caesium-137

  • Medi-Physics/Amersham (formerly 3M)

Iridium-192 LDR

  • Alpha Omega
     
  • Best Industries

Iodine-125

  • Nycomed Amersham 6711
     
  • Nycomed Amersham 6702
     
  • RAPID Strand™
     
  • North American Scientific / Mentor 3631 A/M
     
  • International Isotopes IS-12500
     
  • International Isotopes IS-12501
     
  • Bebig / Uromed Symmetra
     
  • Best Industries 2301
     
  • Mills Biopharmaceuticals 125SH
     
  • Syncor Pharmaceuticals
     
  • Implant Sciences
     
  • International Brachytherapy
     
  • Source Tech
     
  • DRAXIMAGE, Inc.

Palladium

  • Theragenics Theraseed 200
     
  • North American Scientific / Mentor MED3633
     
  • Best Industries 2335
     
  • International Brachytherapy 1031L
     

Several calibrations may be ordered for one insert, for example the Source Holder for Single LDR Seeds, SeeDOS Code 70016, can be calibrated for both Amersham iodine seeds 6711 and 6702.


Rapid Strand, Metastron, and OncoSeed are trademarks of Amersham plc.

 

SOURCE HOLDER COMPATABILITY CHART

This table is provided for your convenience in identifying the proper Source Holder for use with the Seeds and Wires utilized by your facility.

Source Holder, SeeDOS Code

Standard Imaging's Source Holders

Isotopes for Holder

ADCL Calibrations Available

SeeDOS Code, Isotope, Type

70010 Source Holder for HDR Iridium
2.2 mm Opening 		HDR Iridium 80010 , HDR Iridium
70008 Quality Assurance Tool Insert HDR Iridium

None

70020 Source Holder for Caesium
5 mm Opening 		Caesium 80020 , Caesium
70003 Source Holder for Caesium Remote
Afterloading 7.1 mm Opening 		Caesium 80020 , Caesium
70009 Source Holder for LDR Iridium Ribbons LDR Iridium 80025-A , LDR Iridium, Alpha Omega Services
80025-B , Iridium, Best International
70016 Source Holder fo Single LDR Seeds
1.2 mm Opening 		LDR Iridium 80025-A , LDR Iridium, Alpha Omega Services
Iodine 80025-B , Iridium, Best International
80040-A , Iodine, Amersham 6702
80040-B , Iodine, 6711
80040-C , Iodine, Mentor Io Gold
80040-D , Iodine, Best Medical International
80040-E , Iodine, Bebig/Uromed
80040-F , Iodine, Mills
Palladium Biopharmaceuticals/Urocor
80040-G , Iodine, Syncor Pharmaceuticals
80040-H , Iodine, International Isotopes
80035-A , Palladium, Theragenics
80035-B , Palladium, Mentor Pd Gold
80035-C , Palladium, Best Medical International
80035-D , Palladium, IBT/Int. Brachytherapy
70022 Source Holder for LDR Seed Batch Assay Iodine
 		 None
 
Palladium None
70023 Source Holder for I-125 RAPID Strand® Seeds Iodine None
70024 Source Holder for Mick® Cartridge Iodine None
Palladium None
70022 Source Holder for LDR Iridium Wire Coil Iridium Wire None
70026 Source Holder for 5 cc and 10 cc Syringes Metastron® None
Samarium None
70032 Source Holder for Bard EXPRESS Seeding Cartridge Palladium None

NOTE: One source holder may have several calibrations associated with it. For example, a Source Holder for Single LDR Seeds, SeeDOS Code 70016 may have calibrations for Iodine, Palladium, and LDR Iridium.

Rapid Strand, Metastron, and OncoSeed are trademarks of Amersham plc.

If you are interested in any of the products mentioned here, please fill out an Enquiry Form or a Quotation Request Form, so that we may promptly respond to your request.

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Please contact Colin Walters at cwalters@seedos.com if you would like further  information or you have questions

or comments about this web site.
SeeDOS Ltd, 26, The Maltings, Leighton Buzzard, Bedfordshire LU7 4BS, United Kingdom
Tel: +44 1525 850 670  • Fax: +44 1525 850 685